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UCLouvain spin-off · ICTEAM · Limal, Belgium

Resistance leaves
a signal.
We read it in
15 minutes.

Antimicrobial resistance — whichever mechanism, whichever host — is diagnosed 24 to 72 hours after the sample is taken, in a central lab, by trained staff. Fluiscope puts the answer at the point of need: hospital ward, farm, treatment plant. Same platform, three worlds.

Clinical AMR · electrochemical readout Signal acquired
<15 minTime to result
95 / 100%Sensitivity / specificity*
TRL 8Electrochemical core

* First validated assay — carbapenemase detection, CHU UCL Namur. The readout measures enzymatic activity, so the same core extends to other resistance mechanisms.

Clinically validated at CHU UCL Namur — Mont-Godinne Published in J Clin Microbiol & ACS Appl. Bio Mater. Backed by BXVentures · Sopartec · Invest.BW

The diagnostic gap

Waiting for the lab is itself a driver of resistance.

Culture and antibiotic susceptibility testing take one to three days. In the meantime, patients receive broad-spectrum antibiotics, herds are treated preventively, and contaminated effluent is already downstream. The delay isn't an inconvenience — it is the mechanism by which resistance spreads and compounds.

Every hour without an answer is an hour of empirical treatment.

Culture + AST — central lab24–72 h

Trained staff · lab infrastructure · sample transport

Fluiscope — point of need<15 min

No culture step · no trained operator · digital result

What that changes

Isolation decisions during the admission window, not after it. Targeted therapy on day zero. Surveillance data that arrives while it can still inform an action — in a hospital, a slaughterhouse, or a wastewater plant.

One Health positioning

Resistance moves between humans, animals and water. A detection platform should too.

Most diagnostics companies pick one vertical and build a dedicated instrument for it. Fluiscope's electrochemical core and lateral-flow chemistry are the same in all three — what changes is the sample preparation, the antibody and the enzymatic substrate. That holds across resistance mechanisms as much as across sectors: one R&D investment, three regulated markets, and a panel that widens without a new instrument.

Clinical · swabs, isolates, blood cultures Veterinary & agri-food · milk, surfaces, faeces Environment · wastewater, surface water Fluiscope platform LFA + BYG · signal fusion Decision-ready output <15 min · no lab

Clinical

Resistance profiling at the point of care

Screening patients on arrival in ICU and high-risk wards, so isolation and therapy decisions are made in the same shift as the swab. Carbapenemases are the validated entry assay; ESBL, MRSA and further mechanisms follow on the same reader.

Buyer
Hospital microbiology labs, infection control
Pressure
Sciensano / BAPCOC screening guidance, IVDR
Status
First assay clinically validated — Phase 1

Veterinary & agri-food

Screening before the chain, not after

Herd-level resistance screening and surface hygiene swabs along the food chain, where sending samples to a lab is rarely proportionate to the decision being made.

Buyer
Veterinary practices, food producers, integrators
Pressure
EU Reg. 2024/2895, farm-to-fork AMR reduction targets
Status
Assay development — Phase 2

Environment

Resistance surveillance in water

On-site AMR and microbial monitoring at treatment plants and in surface water — the surveillance layer the revised Urban Wastewater Treatment Directive turns from optional to mandatory.

Buyer
Water utilities, treatment plant operators, agencies
Pressure
EU Directive 2024/3019 — AMR monitoring obligations
Status
Pilot partnerships — Phase 2

The platform

Two sensing pillars, one fused answer.

A lateral-flow strip is fast and needs no operator but reads qualitatively. An electrochemical assay is quantitative and sensitive but needs an instrument. Fluiscope runs them together: the strip pre-screens, the electrode confirms, and the reader returns a single interpreted result — for any resistance mechanism the chemistry can be tuned to.

TRL 8 · proven in clinic

Electrochemical sensing — BYG

Disposable printed carbon electrodes read the electrical signature of an enzymatic reaction. Because the readout is the reaction rather than a fixed target, changing the substrate changes the resistance mechanism detected — the instrument stays the same.

  • Se 95% / Sp 100% — carbapenemase assay
  • Handheld potentiostat & multi-channel electronic tongue
  • Peer-reviewed, J Clin Microbiol 2016
TRL 4–5 · assay development

Lateral flow assays — LFA

Capillary migration on a paper strip with gold-nanoparticle-labelled antibodies. Result in minutes, no instrument, no trained operator, unit costs that survive routine screening.

  • Bacteria, viruses, contaminants, physico-chemical
  • Phage-protein recognition for hard targets
  • Peer-reviewed, ACS Appl. Bio Mater. 2024
TRL 3 · integration

Hybrid platform & signal fusion

The differentiator. Qualitative screening and quantitative confirmation in one portable kit, merged into a single interpreted output rather than two results a technician has to reconcile.

  • Modular: swap the assay, keep the reader
  • Connected — results into central databases
  • Core of the IP position now being filed

Sequenced roadmap

Each phase reuses the last one's infrastructure.

The order is deliberate: prove the platform where validation is strongest and the buyer is identified, then extend into markets that regulation is about to create — reusing the same reader, the same chemistry, and most of the same dossier.

Phase 1In progress

Clinical AMR detection

Rapid resistance detection for hospital microbiology labs and infection control teams. Carbapenemase-producing Enterobacteriaceae is the first assay through clinical validation — the reference case that opens the channel for the rest of the panel.

CPE assay validated at CHU UCL NamurIVDR pathwayLicensing discussions
Phase 2Pilots

Environmental & veterinary AMR

AMR surveillance in wastewater and surface water, and resistance screening across the veterinary and agri-food chain. Demand here is created by directive, not by procurement preference.

EU 2024/3019 — UWWTDEU 2024/2895 — agri-foodSTEP pilot partners
Phase 2bNext extension

Full hospital resistance panel

MRSA, ESBL and further mechanisms added to the clinical menu. The highest-leverage extension: same customer, same instrument, same regulatory route as Phase 1 — a wider panel sold into a channel that already exists. Assay work, not platform work.

MRSA · ESBL · beyondInfrastructure reusePanel expansion

Business model

An R&D laboratory that licenses, not a manufacturer that scales.

Fluiscope is built to do the part that is hard to copy — sensor science, assay development, integration — and to hand the rest to partners who already own manufacturing lines, quality systems and distribution in each vertical.

01 / Build

Bioelectronics & LFA lab

Custom sensor development from target to working prototype in weeks to months, for our own roadmap and under contract for industrial partners.

02 / Protect

IP portfolio

Patents and know-how around the hybrid platform and signal fusion, developed with UCLouvain and clinical partners. The asset the licences are written against.

03 / Monetise

Licences & royalties

Upfront fees, development milestones and per-unit royalties from diagnostics manufacturers — one licensee per vertical, revenue that scales without our headcount.

What we deliberately do not do: mass production, sales forces, or regulatory QA in every market. Those are the capital-intensive, low-margin layers our licensees already operate — and the reason a small team can address three verticals at once.

Evidence

Peer-reviewed, then validated in a hospital.

Both pillars of the platform have been published and tested outside our own bench. Carbapenemase detection is the assay that went all the way through clinical evaluation; it is the proof that the readout works on real samples, and the template for every mechanism added after it.

Electrochemical · clinical validation

Evaluation of the BYG Carba Test, an electrochemical assay for rapid detection of carbapenemase-producing Enterobacteriaceae

Yunus S. et al. — Journal of Clinical Microbiology, 2016; 54(2):349–58
Lateral flow · target recognition

Rapid and specific detection of Bacillus cereus using phage protein-based lateral flow assays

Le Brun G. et al. — ACS Appl. Bio Mater., 2024; 7(11):7292–7305
UCLouvain · ICTEAM CHU UCL Namur — Mont-Godinne BXVentures Sopartec Invest.BW Wallonie

Team

Twenty years of sensor research, run as a company.

Grégoire Le Brun

Co-founder · Co-managing director

PhD UCLouvain, MBA Solvay. Seven years of lateral flow assay development across academic and industrial settings.

Sami Yunus

Senior researcher · Electrochemistry

PhD in electronics. Fifteen years in electrochemical sensing; first author of the BYG Carba clinical evaluation.

Nils Préat

Co-managing director · Business

PhD in biosciences, MBA Solvay. Leads commercial strategy, licensing and partnerships across the three verticals.

Work with us

Bring us a target. We build the sensor around it.

Whether you need resistance data faster than your current lab loop allows, a sensor for a contaminant nobody sells a test for, or a platform to license into your own product line — the conversation starts the same way: what are you trying to detect, and what decision depends on it.

  • Pilot sites: hospitals, water utilities, food producers, veterinary practices
  • Licensing: diagnostics manufacturers looking for a validated AMR platform
  • Co-development: Horizon Europe, LIFE, or direct R&D contracts
Fluiscope SRL · Rue de la Station 19, 1300 Limal · Belgium TVA BE1031.611.034 Spin-off of UCLouvain · Supported by Invest.BW and Sopartec www.fluiscope.com

Development-stage technologies. Performance figures refer solely to the BYG Carba carbapenemase assay as evaluated in the referenced clinical study and are not claimed for other resistance mechanisms; lateral flow and hybrid configurations are at TRL 3–5 and are not CE-IVD marked.